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Every Cure Inc

EIN 92-0240717 · Philadelphia, PA

Public records show a registered, tax-exempt organization in good standing.

LegitimacyPassesRegistration and standingFinancial healthStrong100 out of 100GovernanceStrong100 out of 100Impact evidenceDescribes programsHow well its results are evidenced

What it says it does

EVERY CURE IS A NONPROFIT INITIATIVE ON A MISSION TO UNLOCK THE FULL POTENTIAL OF EXISTING MEDICINES TO TREAT EVERY DISEASE AND EVERY PATIENT THEY POSSIBLY CAN.

Income
$54.5 million
Spending
$7.4 million
Spent on programs
85%
Reserves
78.5 months of spending
Largest source of income
donations and private grants, 83%
Employees
16
Volunteers
9
Highest pay
$465,529, co-founder,ceo (comp 9/23-12/24)

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Financial health

Strong: 100 out of 100. Higher than 92% of charities in its peer group (medical research, $10m to $100m).

  • Reserves

    35 of 35

    Spendable reserves would cover 78.5 months of spending.

  • Debt

    20 of 20

    It owes 5% of what it owns.

  • Living within its means

    15 of 15

    Income exceeded spending by 86% of income.

  • Income trend

    15 of 15

    Income rose 2129% on the year before.

  • Spending floor

    15 of 15

    85% of spending went to programs and raising each dollar of donations cost 0 cents.

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Governance

Strong: 100 out of 100. Higher than 45% of charities in its peer group (medical research, $10m to $100m).

  • Independent board

    25 of 25

    6 of 8 voting board members are independent.

  • Conflict of interest policy

    15 of 15

    Has a written conflict of interest policy.

  • Whistleblower policy

    8 of 8

    Has a written whistleblower policy.

  • Record keeping policy

    7 of 7

    Has a written policy on keeping and destroying records.

  • Board minutes

    5 of 5

    Keeps minutes of board meetings.

  • Board sees the tax return

    10 of 10

    Gave the board a copy of this return before filing it.

  • Pay set independently

    5 of 5

    Sets its chief executive's pay through independent review and comparison.

  • Independent check of accounts

    15 of 15

    Its accounts were audited by an independent accountant.

  • No reported misuse

    10 of 10

    Reports no diversion of assets, excess benefits or loans to insiders.

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Impact evidence

Describes programs. Its tax return describes what it does but we have found no measurable results in it.

Programs described in its return (3)
  1. $4.3 million spent. 1. AI TOOL DEVELOPMENT AND OPEN-SOURCE INITIATIVE (TECHNOLOGICAL INNOVATION)(CONTINUED ON SCHEDULE O)IN 2024, EVERY CURE'S TECHNICAL TEAM BUILT A ROBUST, SCALABLE PLATFORM TO SYSTEMATICALLY IDENTIFY HIGH-POTENTIAL DRUG REPURPOSING OPPORTUNITIES. THE TEAM CURATED COMPREHENSIVE DRUG AND DISEASE LISTS BUILDING ON EXISTING ONTOLOGIES, ESTABLISHED A POWERFUL EXPERIMENTATION AND EVALUATION INFRASTRUCTURE, AND BEGAN THE INTEGRATION OF MULTIPLE PUBLIC AND PROPRIETARY BIOMEDICAL KNOWLEDGE GRAPHS INTO A HARMONIZED ARCHITECTURE. USING THIS FOUNDATION, THEY DEVELOPED AND STABILIZED A PIPELINE THAT ENABLED RAPID, LARGE-SCALE PREDICTION OF DRUG-DISEASE MATCHES, WHICH THEN GO FOR SYSTEMATIC REVIEW BY EVERY CURE'S MEDICAL TEAM. OVER THE COURSE OF THE YEAR, THE TEAM EXECUTED AND LOGGED EIGHT EXPERIMENTS TO VALIDATE AND REFINE MODEL PERFORMANCE, SIGNIFICANTLY ACCELERATING EXPERIMENTAL THROUGHPUT INTO 2025. WE ALSO OBTAINED RIGHTS TO SEVERAL PROPRIETARY DATASETS TO IMPROVE PERFORMANCE IN DIFFERENT STAGES IN THE PIPELINE.
  2. $1.8 million spent. 2. DRUG REPURPOSING RESEARCH AND DEVELOPMENT (SCIENTIFIC APPLICATION)(CONTINUED ON SCHEDULE O)EVERY CURE, INC. SAVES AND IMPROVES LIVES BY REPURPOSING DRUGS. DISCOVERY OF DRUG REPURPOSING OPPORTUNITIES OCCURS USING BOTH EXISTING KNOWLEDGE AND AI-GENERATED FINDINGS. DRUG REPURPOSING EFFORTS ENCOMPASS THE CORE SCIENTIFIC AND MEDICAL EFFORTS TO MOVE A DRUG REPURPOSING CONCEPT FROM DISCOVERY TO CLINICAL APPLICATION. ADVANCEMENT OF THE MOST PROMISING CANDIDATES MAY INCLUDE MANAGING PRE-CLINICAL STUDIES, REAL-WORLD EVIDENCE REVIEW AND CLINICAL TRIALS. IN 2024, EVERY CURE ESTABLISHED A WORLD CLASS MEDICAL TEAM, A TECHNICAL ADVISORY COUNCIL (TAC) AND A SCIENTIFIC ADVISORY COUNCIL (SAC) TO PROVIDE OVERSIGHT AND VALIDATE DISCOVERIES. THE TEAM ESTABLISHED BEST PRACTICE FOR VETTING REPURPOSING OPPORTUNITIES, LEADING TO THE IDENTIFICATION OF FOUR PROMISING REPURPOSED TREATMENTS ENDORSED BY THE SAC AS WELL AS IDENTIFICATION OF POTENTIAL THERAPEUTIC OPPORTUNITIES FOR LONG COVID. THE CANDIDATE DRUG REPURPOSING OPPORTUNITIES SPANNED CONDITIONS FROM A COMMON CANCER TO A RARE NEURODEVELOPMENTAL CONDITIONS. AS A RESULT OF THESE EFFORTS, MULTIPLE INDIVIDUALS SHARED STORIES OF HOW THEIR LIVES WERE SAVED AND IMPROVED BY REPURPOSED DRUGS.
  3. $144,749 spent. 3. EDUCATION AND AWARENESS-RAISING ON DRUG REPURPOSING(CONTINUED ON SCHEDULE O)EVERY CURE, INC. EDUCATES PHYSICIANS, RESEARCHERS, PATIENTS, POLICYMAKERS, AND THE GENERAL PUBLIC ABOUT THE POTENTIAL FOR DRUG REPURPOSING TO ACCELERATE CURES. EDUCATION AND OUTREACH ARE CENTRAL TO CREATING A SHIFT IN MEDICINE, WHERE EXISTING THERAPIES ARE FULLY LEVERAGED FOR DISEASES BEYOND THEIR ORIGINAL APPROVALS.SPECIFIC ACCOMPLISHMENTS INCLUDE: EDUCATIONAL PROGRAMS AND WORKSHOPS: ORGANIZED SCIENTIFIC CONVENINGS SUCH AS THE CHAN ZUCKERBERG INITIATIVE (CZI)-SUPPORTED WORKSHOP ON RARE DISEASE DRUG REPURPOSING, WHICH BROUGHT TOGETHER LEADING EXPERTS ACROSS ACADEMIA, INDUSTRY, AND GOVERNMENT TO SHARE KNOWLEDGE AND DEFINE COLLABORATIVE PATHWAYS. PROFESSIONAL OUTREACH: DISSEMINATED FINDINGS THROUGH PRESENTATIONS AT INTERNATIONAL SCIENTIFIC MEETINGS, INVITED TALKS AT RESEARCH INSTITUTIONS, AND PUBLICATION OF EDUCATIONAL CONTENT IN PROFESSIONAL OUTLETS TO INCREASE AWARENESS AMONG PHYSICIANS AND SCIENTISTS. PATIENT AND PUBLIC ENGAGEMENT: LEVERAGED MEDIA EXPOSURE, SOCIAL MEDIA CAMPAIGNS, AND DIRECT PATIENT COMMUNITY ENGAGEMENT TO INCREASE UNDERSTANDING OF DRUG REPURPOSING OPPORTUNITIES, EMPOWERING PATIENTS TO DISCUSS POTENTIAL OPTIONS WITH THEIR PHYSICIANS. ROADMAP DEVELOPMENT: ADVANCED THE ROADMAP INITIATIVE, A FRAMEWORK FOR HOW TO SYSTEMATICALLY IDENTIFY AND VALIDATE REPURPOSING OPPORTUNITIES FOR RARE DISEASES, PROVIDING A REPLICABLE RESOURCE FOR THE FIELD. DIGITAL AWARENESS: REACHED MILLIONS THROUGH MEDIA FEATURES AND SOCIAL MEDIA, HIGHLIGHTING THE STORY OF DRUG REPURPOSING AND EVERY CURE'S MISSION, INCREASING VISIBILITY AND ENGAGEMENT WITH OUR WORK.THROUGH THESE ACTIVITIES, EVERY CURE HAS CREATED A FOUNDATION OF KNOWLEDGE AND AWARENESS THAT WILL HELP TO ACCELERATE THE PACE OF DRUG REPURPOSING ACROSS THE HEALTHCARE ECOSYSTEM.

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Legitimacy checks

  1. Is it registered with the IRS? Passed.

    Listed in the IRS master file of tax-exempt organizations as a 501(c)(3) charitable organization.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  2. Has the IRS revoked its tax-exempt status? Passed.

    Not on the IRS automatic revocation list.

    Source: Automatic revocation of exemption list, Internal Revenue Service, file dated October 13, 2026.

  3. Are donations tax-deductible? Passed.

    On the IRS list of organizations eligible to receive tax-deductible contributions.

    Source: Publication 78 data: organizations eligible for tax-deductible contributions, Internal Revenue Service, file dated October 13, 2026.

  4. Is it keeping up with its IRS filings? Passed.

    Most recent return on file covers the year ending December 2025.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  5. How long has it been tax-exempt? Passed.

    Recognized by the IRS since May 2023.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  6. Is it in good standing with state regulators? Passed.

    Not on California's list of charities barred from soliciting. Other states are not yet checked.

    Source: May Not Operate or Solicit for Charitable Purposes list, California Attorney General, Registry of Charities and Fundraisers, file dated October 21, 2026.

Ratings and checks are our reading of public records, using the published method. They are not a statement about anyone's honesty. If you work for this organization, you can send corrections or results, confirm you want gifts through Veridonate, or ask to be removed from giving.