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Combinedbrain Inc

EIN 83-1825692 · Brentwood, TN

Public records show a registered, tax-exempt organization in good standing.

LegitimacyPassesRegistration and standingFinancial healthFair64 out of 100GovernanceFair65 out of 100Impact evidenceDescribes programsHow well its results are evidenced

What it says it does

THE CONSORTIUM FOR OUTCOME MEASURES AND BIOMARKERS FOR NEURODEVELOPMENTAL DISORDERS IS A NON-PROFIT ORGANIZATION DEVOTED TO SPEEDING THE PATH TO CLINICAL TREATMENTS FOR PEOPLE WITH RARE GENETIC NEURODEVELOPMENTAL DISORDERS BY POOLING EFFORTS, STUDIES, AND DATA.

Income
$1.2 million
Spending
$1.3 million
Spent on programs
84%
Reserves
3.9 months of spending
Largest source of income
donations and private grants, 48%
Employees
10
Volunteers
16
Highest pay
$66,667, executive director

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Financial health

Fair: 64 out of 100. Higher than 25% of charities in its peer group (diseases, $1m to $10m).

  • Reserves

    20 of 35

    Spendable reserves would cover 3.9 months of spending.

  • Debt

    10 of 20

    It owes 34% of what it owns.

  • Living within its means

    4 of 15

    Spending exceeded income by 9% of income.

  • Income trend

    15 of 15

    Income rose 5% on the year before.

  • Spending floor

    15 of 15

    84% of spending went to programs and raising each dollar of donations cost 1 cents.

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Governance

Fair: 65 out of 100. Higher than 13% of charities in its peer group (diseases, $1m to $10m).

  • Independent board

    25 of 25

    13 of 13 voting board members are independent.

  • Conflict of interest policy

    0 of 15

    Reports no written conflict of interest policy.

  • Whistleblower policy

    0 of 8

    Reports no written whistleblower policy.

  • Record keeping policy

    0 of 7

    Reports no written policy on keeping and destroying records.

  • Board minutes

    5 of 5

    Keeps minutes of board meetings.

  • Board sees the tax return

    10 of 10

    Gave the board a copy of this return before filing it.

  • Pay set independently

    0 of 5

    Reports no independent review process for its chief executive's pay.

  • Independent check of accounts

    15 of 15

    Its accounts were audited by an independent accountant.

  • No reported misuse

    10 of 10

    Reports no diversion of assets, excess benefits or loans to insiders.

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Impact evidence

Describes programs. Its tax return describes what it does but we have found no measurable results in it.

Programs described in its return (2)
  1. $725,850 spent. BIOREPOSITORY: IN A 2024 STRATEGIC PLANNING PROCESS, SURVEYS WERE SENT SEPARATELY TO THE CLINICAL ADVISORY BOARD (CAB), SCIENTIFIC ADVISORY BOARD (SAB), PATIENT ADVOCACY ADVISORY BOARD (PAB) AND INDUSTRY ADVISORY BOARD (IAB), AND EACH INDEPENDENTLY PRIORITIZED BIOMARKER STUDIES ABOVE ALL OTHER EFFORTS. ACROSS ALL OF THE ADVISORY BOARDS, NATURAL HISTORY WAS THE SECOND MOST COMMONLY CHOSEN AREA OF CONCERN, BUT AMONGST THE PAB, CONSTRUCTION OF RESEARCH STRATEGIC PLANS WAS THE SECOND HIGHEST PRIORITY. BASED ON THESE PRIORITIES, COMBINEDBRAIN HAS FOCUSED EXTENSIVE EFFORTS ON HOSTING A BIOREPOSITORY AND ORGANIZING PRE-COMPETITIVE BIOMARKER PROJECTS. THE REPOSITORY IS FUNDED AND GOVERNED BY MEMBER PAGS.
  2. $362,141 spent. RENT A NEUROSCIENTIST: TO RESPOND TO THE PAB REQUEST FOR HELP WITH STRATEGIC RESEARCH PLANS, COMBINEDBRAIN HIRES POST-DOCTORAL FELLOWS, AND STUDENT INTERNS. THESE TEAMS STAFF THE RENT-A-BRAIN PROGRAM, WHICH ASSISTS WITH THE ROADSHOW, BUT PRIMARILY SERVES AS PART-TIME SCIENTIFIC OFFICERS FOR MEMBER PAGS. WHEN REQUESTED, THESE TEAMS REVIEW THE LANDSCAPE OF DRUG DEVELOPMENT FOR A GIVEN DISORDER IN AN OBJECTIVE AND ECONOMICAL WAY, RESULTING IN A SERIES OF RECOMMENDATIONS FOR MOVING AS FAST AS POSSIBLE FROM DIAGNOSIS TO AN FDA-APPROVED DRUG. THE RENT-A-BRAIN TEAMS ALSO ASSIST PAGS WITH GRANT APPLICATIONS, GRANT REVIEWS, LITERATURE SUMMARIES, DISEASE CONCEPT STUDIES, AND MANUSCRIPT PREPARATION. RENTA-BRAIN ACTIVITIES VARY WIDELY, AS DEMANDED BY THE PAGS AND ADVISORY BOARDS. FOR EXAMPLE, ONE TEAM HAS PREPARED SCIENTIFIC RATIONALE FOR ADDING MEMBER DISORDERS TO DIAGNOSTIC MICROARRAYS, ANOTHER HAS PREPARED APPLICATIONS FOR ICD-10 CODES, AND ANOTHER HAS DRAFTED A SURVEY OF TOILETING ABILITIES TO BE PILOTED ACROSS NEURODEVELOPMENTAL DISORDERS, AMONGST MANY OTHER PROJECTS.

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Legitimacy checks

  1. Is it registered with the IRS? Passed.

    Listed in the IRS master file of tax-exempt organizations as a 501(c)(3) charitable organization.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  2. Has the IRS revoked its tax-exempt status? Passed.

    Not on the IRS automatic revocation list.

    Source: Automatic revocation of exemption list, Internal Revenue Service, file dated October 13, 2026.

  3. Are donations tax-deductible? Passed.

    On the IRS list of organizations eligible to receive tax-deductible contributions.

    Source: Publication 78 data: organizations eligible for tax-deductible contributions, Internal Revenue Service, file dated October 13, 2026.

  4. Is it keeping up with its IRS filings? Passed.

    Most recent return on file covers the year ending December 2024.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  5. How long has it been tax-exempt? Passed.

    Recognized by the IRS since October 2020.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  6. Is it in good standing with state regulators? Passed.

    Not on California's list of charities barred from soliciting. Other states are not yet checked.

    Source: May Not Operate or Solicit for Charitable Purposes list, California Attorney General, Registry of Charities and Fundraisers, file dated October 21, 2026.

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