Jaeb Center for Health Research Inc
Public records show a registered, tax-exempt organization in good standing.
Points to look into
- It owes more than it owns.
These come from the organization's own tax return. There may be a good explanation; ask the charity.
What it says it does
OUR MISSION IS TO EXPAND SCIENTIFIC KNOWLEDGE AND IMPROVE PUBLIC HEALTH BY DESIGNING AND CONDUCTING WORLD-CLASS CLINICAL TRIALS AND EPIDEMIOLOGIC RESEARCH.
- Income
- $58.7 million
- Spending
- $60.0 million
- Spent on programs
- 86%
- Reserves
- -1.2 months of spending
- Largest source of income
- fees for its services, 34%
- Employees
- 187
- Volunteers
- 4
- Highest pay
- $637,538, medical director
Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate
Financial health
Weak: 38 out of 100.
Reserves
0 of 35Spendable reserves are negative: it owes or has committed more than it holds.
Debt
0 of 20It owes 122% of what it owns.
Living within its means
8 of 15Spending exceeded income by 2% of income.
Income trend
15 of 15Income rose 14% on the year before.
Spending floor
15 of 1586% of spending went to programs and raising each dollar of donations cost 0 cents.
Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate
Governance
Strong: 100 out of 100.
Independent board
25 of 254 of 5 voting board members are independent.
Conflict of interest policy
15 of 15Has a written conflict of interest policy.
Whistleblower policy
8 of 8Has a written whistleblower policy.
Record keeping policy
7 of 7Has a written policy on keeping and destroying records.
Board minutes
5 of 5Keeps minutes of board meetings.
Board sees the tax return
10 of 10Gave the board a copy of this return before filing it.
Pay set independently
5 of 5Sets its chief executive's pay through independent review and comparison.
Independent check of accounts
15 of 15Its accounts were audited by an independent accountant.
No reported misuse
10 of 10Reports no diversion of assets, excess benefits or loans to insiders.
Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate
Impact evidence
Describes programs. Its tax return describes what it does but we have found no measurable results in it.
Programs described in its return (1)
- $51.8 million spent. DURING 2025, JCHR WAS ENGAGED IN 61 CLINICAL STUDIES, WHICH CULMINATED IN 53 SCIENTIFIC PUBLICATIONS AND 58 PRESENTATIONS AT PROMINENT NATIONAL AND INTERNATIONAL CONFERENCES. IN 2025, JCHR RECEIVED GRANTS FROM THE NATIONAL INSTITUTES OF HEALTH (6), HELMSLEY CHARITABLE TRUST (7), BREAKTHROUGH T1D (5), FOUNDATION FIGHTING BLINDNESS (6), CYSTIC FIBROSIS FOUNDATION (4), FOOD AND DRUG ADMINISTRATION (1), AND NATIONAL INSTITUTE FOR HEALTH AND CARE RESEARCH (1). COLLABORATIONS WITH INDUSTRY CONTINUE TO BE AN INTEGRAL PART OF OUR WORK. JCHR WAS ENGAGED IN COLLABORATIONS WITH 14 INDUSTRY PARTNERS SPANNING 21 STUDIES, INCLUDING 11 INVESTIGATOR INITIATED STUDIES. SEVERAL STUDIES ARE FUNDED BY MULTIPLE SOURCES. FOR EXAMPLE, ONE CLINICAL TRIAL EVALUATING FENOFIBRATE FOR DIABETIC RETINOPATHY IS A LARGE COLLABORATION WITH FUNDS PROVIDED BY THE NATIONAL INSTITUTES OF HEALTH (NATIONAL EYE INSTITUTE AND NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASE), BREAKTHROUGH T1D, HELMSLEY CHARITABLE TRUST, AND ROCHE. JCHR ALSO SELF-FUNDED ONE STUDY AND NUMEROUS STATISTICAL ANALYSIS PROJECTS USING DATASETS FROM PREVIOUSLY COMPLETED STUDIES. AMONG APPROXIMATELY 2,705 ENTITIES RECEIVING NIH FUNDING IN 2025, JCHR RANKS IN THE TOP 8 PERCENT. OUT OF APPROXIMATELY 59,500 NIH GRANTS AWARDED IN 2025, JCHR HAD THE 108TH- (TOP 0.18 PERCENT) AND 202ND - (TOP 0.34 PERCENT) LARGEST GRANTS (SOURCE: BLUE RIDGE INSTITUTE FOR MEDICAL RESEARCH, 2025). DURING 2025, JCHR'S RESEARCH EFFORTS FOCUSED ON THREE MAIN THERAPEUTIC AREAS: DIABETES RESEARCH: A MULTITUDE OF CLINICAL TRIALS AND OBSERVATIONAL STUDIES INVOLVED RESEARCH IN TYPE 1, TYPE 2, AND GESTATIONAL DIABETES, ENCOMPASSING PEDIATRIC AND ADULT POPULATIONS INCLUDING MATERNAL-FETAL HEALTH OUTCOMES. MANY STUDIES FOCUSED ON ADVANCING TECHNOLOGY-DRIVEN DIABETES MANAGEMENT WITH ARTIFICIAL PANCREAS SYSTEMS, INSULIN PUMPS, AND CONTINUOUS GLUCOSE MONITORS (CGMS), WHILE OTHERS INVOLVED THE ASSESSMENT OF GROWING ADJUNCT THERAPY USE IN DIABETES CARE AS WELL AS INTERVENTIONAL STRATEGIES TO PRESERVE ENDOGENOUS INSULIN PRODUCTION, UTILIZE INHALED INSULIN, OR LEVERAGE ENHANCED PATIENT AND CAREGIVER EDUCATION INCLUDING AROUND EXERCISE REGIMENS TO IMPROVE GLUCOSE CONTROL. EYE DISEASE RESEARCH: JCHR CONTINUED ITS ROLE AS A COORDINATING CENTER FOR THREE MAJOR NETWORKS AS WELL AS INDIVIDUAL EYE DISEASE STUDIES: 1. THE DRCR RETINA NETWORK, INVESTIGATING DIABETIC RETINOPATHY, AGE-RELATED MACULAR DEGENERATION, AND OTHER RETINAL DISEASES. 2. THE PEDIATRIC EYE DISEASE INVESTIGATOR GROUP (PEDIG), FOCUSING ON A WIDE RANGE OF CHILDHOOD EYE CONDITIONS. 3. THE FOUNDATION FIGHTING BLINDNESS CONSORTIUM, DEDICATED TO STUDYING RARE RETINAL DISEASES. ADDITIONALLY, JCHR IS CURRENTLY COORDINATING A STUDY ON LONG-TERM OUTCOMES FOLLOWING CORNEAL TRANSPLANTATION. CYSTIC FIBROSIS RESEARCH: JCHR'S GROWING RESEARCH PORTFOLIO INCLUDES A TRIAL INVESTIGATING USE OF THE BIONIC PANCREAS SYSTEM TO MANAGE CYSTIC FIBROSIS-RELATED DIABETES AS WELL AS OBSERVATIONAL STUDIES SEEKING TO BETTER CHARACTERIZE OTHER PHYSIOLOGICAL AND METABOLIC COMPLICATIONS OF CYSTIC FIBROSIS. KEY STUDIES EXAMINED THE IMPACT OF NUTRITION, MUSCLE STRENGTH, AND GLUCOSE MONITORING TECHNOLOGIES ON LUNG FUNCTION AND OVERALL HEALTH OUTCOMES IN INDIVIDUALS WITH CYSTIC FIBROSIS.
Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate
Legitimacy checks
Is it registered with the IRS? Passed.
Listed in the IRS master file of tax-exempt organizations as a 501(c)(3) charitable organization.
Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.
Has the IRS revoked its tax-exempt status? Passed.
Not on the IRS automatic revocation list.
Source: Automatic revocation of exemption list, Internal Revenue Service, file dated November 6, 2026.
Are donations tax-deductible? Passed.
On the IRS list of organizations eligible to receive tax-deductible contributions.
Source: Publication 78 data: organizations eligible for tax-deductible contributions, Internal Revenue Service, file dated October 13, 2026.
Is it keeping up with its IRS filings? Passed.
Most recent return on file covers the year ending December 2025.
Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.
How long has it been tax-exempt? Passed.
Recognized by the IRS since November 1998.
Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.
Is it in good standing with state regulators? Passed.
Not on California's list of charities barred from soliciting. Other states are not yet checked.
Source: May Not Operate or Solicit for Charitable Purposes list, California Attorney General, Registry of Charities and Fundraisers, file dated November 4, 2026.
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