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American Society for Clinical Investigation Inc

EIN 52-0847477 · Ann Arbor, MI

Public records show a registered, tax-exempt organization in good standing.

LegitimacyPassesRegistration and standingFinancial healthStrong97 out of 100GovernanceStrong100 out of 100Impact evidenceDescribes programsHow well its results are evidenced

What it says it does

THE AMERICAN SOCIETY FOR CLINICAL INVESTIGATION SEEKS TO SUPPORT THE SCIENTIFIC EFFORTS, EDUCATIONAL NEEDS, AND CLINICAL ASPIRATIONS OF PHYSICIAN-SCIENTISTS TO IMPROVE THE HEALTH OF ALL PEOPLE.

Income
$8.0 million
Spending
$7.9 million
Spent on programs
89%
Reserves
19.5 months of spending
Largest source of income
fees for its services, 78%
Employees
43
Volunteers
13
Highest pay
$435,805, executive director

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Financial health

Strong: 97 out of 100.

  • Reserves

    35 of 35

    Spendable reserves would cover 19.5 months of spending.

  • Debt

    20 of 20

    It owes 6% of what it owns.

  • Living within its means

    12 of 15

    Income exceeded spending by 2% of income.

  • Income trend

    15 of 15

    Income rose 2% on the year before.

  • Spending floor

    15 of 15

    89% of spending went to programs and raising each dollar of donations cost 0 cents.

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Governance

Strong: 100 out of 100.

  • Independent board

    25 of 25

    10 of 13 voting board members are independent.

  • Conflict of interest policy

    15 of 15

    Has a written conflict of interest policy.

  • Whistleblower policy

    8 of 8

    Has a written whistleblower policy.

  • Record keeping policy

    7 of 7

    Has a written policy on keeping and destroying records.

  • Board minutes

    5 of 5

    Keeps minutes of board meetings.

  • Board sees the tax return

    10 of 10

    Gave the board a copy of this return before filing it.

  • Pay set independently

    5 of 5

    Sets its chief executive's pay through independent review and comparison.

  • Independent check of accounts

    15 of 15

    Its accounts were audited by an independent accountant.

  • No reported misuse

    10 of 10

    Reports no diversion of assets, excess benefits or loans to insiders.

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Impact evidence

Describes programs. Its tax return describes what it does but we have found no measurable results in it.

Programs described in its return (2)
  1. $4.5 million spent. THIS SOCIETY IS ORGANIZED AND OPERATED EXCLUSIVELY FOR EDUCATIONAL AND SCIENTIFIC PURPOSES AND FOR NO OTHER PURPOSE. THE OBJECTIVES OF THE CORPORATION, AS EXPRESSED IN THE 1908 CONSTITUTION ARE: THE ADVANCEMENT OF MEDICAL SCIENCE; THE CULTIVATION OF CLINICAL RESEARCH BY THE METHODS OF THE NATURAL SCIENCES; THE CORRELATION OF SCIENCE WITH THE ART OF MEDICAL PRACTICE; THE ENCOURAGEMENT OF SCIENTIFIC INVESTIGATION BY THE MEDICAL PRACTITIONER; AND THE DIFFUSION OF A SCIENTIFIC SPIRIT AMONG ITS MEMBERS. TO THIS END THE SOCIETY PUBLISHES TWO BIOMEDICAL JOURNALS, THE JOURNAL OF CLINICAL INVESTIGATION AND JCI INSIGHT, BOTH PEER-REVIEWED BIOMEDICAL RESEARCH JOURNALS THAT ARE AVAILABLE WORLDWIDE TO MEMBERS AND NON MEMBERS ALIKE, WITH ALL RESEARCH CONTENT FREELY AVAILABLE WITHOUT RESTRICTION OF ANY KIND. IN 2025, THE ASCI PUBLISHED 499 RESEARCH ARTICLES IN THE JOURNAL OF CLINICAL INVESTIGATION AND 522 RESEARCH ARTICLES IN JCI INSIGHT.
  2. $2.5 million spent. THE ASCI IS DEDICATED TO THE ADVANCEMENT OF RESEARCH THAT EXTENDS OUR UNDERSTANDING AND IMPROVES THE TREATMENT OF HUMAN DISEASES, AND MEMBERS ARE COMMITTED TO MENTORING FUTURE GENERATIONS OF PHYSICIAN-SCIENTISTS. THE ASCI CONSIDERS THE NOMINATIONS OF SEVERAL HUNDRED PHYSICIAN-SCIENTISTS FROM THE UNITED STATES AND ABROAD EACH YEAR AND ELECTS UP TO 100 NEW MEMBERS EACH YEAR FOR THEIR SIGNIFICANT RESEARCH ACCOMPLISHMENTS. AN ANNUAL MEETING IS HELD TO HONOR THE NEWLY ELECTED MEMBERS, TO FOSTER THE DIFFUSION OF SCIENTIFIC SPIRIT AMONG MEMBERS, AND TO MENTOR YOUNG INVESTIGATORS.

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Legitimacy checks

  1. Is it registered with the IRS? Passed.

    Listed in the IRS master file of tax-exempt organizations as a 501(c)(3) charitable organization.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated September 7, 2026.

  2. Has the IRS revoked its tax-exempt status? Passed.

    Not on the IRS automatic revocation list.

    Source: Automatic revocation of exemption list, Internal Revenue Service, file dated September 30, 2026.

  3. Are donations tax-deductible? Passed.

    On the IRS list of organizations eligible to receive tax-deductible contributions.

    Source: Publication 78 data: organizations eligible for tax-deductible contributions, Internal Revenue Service, file dated September 10, 2026.

  4. Is it keeping up with its IRS filings? Passed.

    Most recent return on file covers the year ending December 2025.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated September 7, 2026.

  5. How long has it been tax-exempt? Passed.

    Recognized by the IRS since December 1992.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated September 7, 2026.

  6. Is it in good standing with state regulators? Passed.

    Not on California's list of charities barred from soliciting. Other states are not yet checked.

    Source: May Not Operate or Solicit for Charitable Purposes list, California Attorney General, Registry of Charities and Fundraisers, file dated October 7, 2026.

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