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Sanders Tri-Institutional Therapeut Discovery Institute Inc Co Weill C

EIN 46-3673346 · New York, NY

Public records show a registered, tax-exempt organization in good standing.

LegitimacyPassesRegistration and standingFinancial healthWeak34 out of 100GovernanceGood80 out of 100Impact evidenceDescribes programsHow well its results are evidenced

What it says it does

TO FURTHER AND IMPROVE HEALTH AND THE DIAGNOSIS, PREVENTION AND TREATMENT OF DISEASE THROUGH RESEARCH, GENERATE INNOVATIVE PROOF-OF-CONCEPT STUDIES, AND ADVANCE THE SCIENTIFIC ACTIVITIES OF THE CONTROLLING INSTITUTIONS. (CONTINUED ON SCHEDULE O)THE SANDERS TRI-INSTITUTIONAL THERAPEUTICS DISCOVERY INSTITUTE, INC. WAS ORGANIZED AND IS OPERATED AS AN INDEPENDENT, NON-PROFIT CORPORATION, CONTROLLED BY LEADING NOT-FOR-PROFIT ACADEMIC, MEDICAL AND RESEARCH INSTITUTIONS, TO FURTHER AND IMPROVE HEALTH AND THE DIAGNOSIS, PREVENTION AND TREATMENT OF DISEASE THROUGH TRANSLATIONAL RESEARCH, GENERATE INNOVATIVE PROOF-OF-CONCEPT STUDIES, AND ADVANCE THE SCIENTIFIC ACTIVITIES OF THE CONTROLLING INSTITUTIONS (MEMORIAL SLOAN KETTERING CANCER CENTER, THE ROCKEFELLER UNIVERSITY, AND WEILL CORNELL MEDICAL COLLEGE) FACULTY, FELLOWS AND STUDENTS IN ASPECTS OF TRANSLATIONAL RESEARCH, CHEMISTRY, PHARMACOLOGY, AND DRUG DISCOVERY.

Income
$16.6 million
Spending
$16.6 million
Spent on programs
93%
Reserves
-0.5 months of spending
Largest source of income
fees for its services, 98%
Employees
32
Volunteers
0
Highest pay
$7.0 million, board member

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Financial health

Weak: 34 out of 100. Higher than 6% of charities in its peer group (medical research, $10m to $100m).

  • Reserves

    0 of 35

    Spendable reserves are negative: it owes or has committed more than it holds.

  • Debt

    2 of 20

    It owes 100% of what it owns.

  • Living within its means

    12 of 15

    Income exceeded spending by 0% of income.

  • Income trend

    5 of 15

    Income fell 11% on the year before.

  • Spending floor

    15 of 15

    93% of spending went to programs and raising each dollar of donations cost 0 cents.

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Governance

Good: 80 out of 100. Higher than 12% of charities in its peer group (medical research, $10m to $100m).

  • Independent board

    5 of 25

    0 of 9 voting board members are independent.

  • Conflict of interest policy

    15 of 15

    Has a written conflict of interest policy.

  • Whistleblower policy

    8 of 8

    Has a written whistleblower policy.

  • Record keeping policy

    7 of 7

    Has a written policy on keeping and destroying records.

  • Board minutes

    5 of 5

    Keeps minutes of board meetings.

  • Board sees the tax return

    10 of 10

    Gave the board a copy of this return before filing it.

  • Pay set independently

    5 of 5

    Sets its chief executive's pay through independent review and comparison.

  • Independent check of accounts

    15 of 15

    Its accounts were audited by an independent accountant.

  • No reported misuse

    10 of 10

    Reports no diversion of assets, excess benefits or loans to insiders.

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Impact evidence

Describes programs. Its tax return describes what it does but we have found no measurable results in it.

Programs described in its return (2)
  1. $12.1 million spent. THE SANDERS TRI-INSTITUTIONAL THERAPEUTICS DISCOVERY INSTITUTE, A PARTNERSHIP AMONG THREE WORLD-RENOWNED SCIENTIFIC AND MEDICAL INSTITUTIONS, WORKS TO MORE EFFECTIVELY DEVELOP THERAPEUTICS THAT ARISE FROM DISCOVERIES MADE IN BASIC SCIENCE LABS. WITH A FOCUS ON EARLY-STAGE DRUG DISCOVERY, THE INSTITUTE PROVIDES EXPERTISE IN MEDICINAL CHEMISTRY AND COMPOUND SCREENING, AND CONDUCTS PROOF OF CONCEPT STUDIES NEEDED TO DEMONSTRATE THAT DRUG CANDIDATES CAN SUCCESSFULLY ALTER THE COURSE OF A DISEASE. SPECIFIC RESEARCH PROJECTS FOCUS ON ALZHEIMERS DISEASE, SICKLE CELL, OSTEOPOROSIS, LYSOSOMAL, LIPID DEPOSITS, PARKINSON'S AND BASAL CELL CARCINOMA.
  2. $3.3 million spent. THE INSTITUTE FACILITATES MORE EFFICIENT SHARING OF CORE FACILITIES BETWEEN THE THREE PARTNER INSTITUTIONS AND FORMS INDUSTRY PARTNERSHIPS WITH PHARMACEUTICAL AND BIOTECH COMPANIES TO FURTHER ADVANCE DRUG RESEARCH. IT SEEKS TO CREATE INTELLECTUAL PROPERTY THAT CAN BE FURTHER DEVELOPED BY AN OPEN FIELD OF INDUSTRY COLLABORATORS. THE MAJORITY OF SUCH SERVICES RELATE TO MEDICINAL CHEMISTRY SUPPORT.

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Legitimacy checks

  1. Is it registered with the IRS? Passed.

    Listed in the IRS master file of tax-exempt organizations as a 501(c)(3) charitable organization.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated September 7, 2026.

  2. Has the IRS revoked its tax-exempt status? Passed.

    Not on the IRS automatic revocation list.

    Source: Automatic revocation of exemption list, Internal Revenue Service, file dated September 30, 2026.

  3. Are donations tax-deductible? Passed.

    On the IRS list of organizations eligible to receive tax-deductible contributions.

    Source: Publication 78 data: organizations eligible for tax-deductible contributions, Internal Revenue Service, file dated September 10, 2026.

  4. Is it keeping up with its IRS filings? Passed.

    Most recent return on file covers the year ending December 2024.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated September 7, 2026.

  5. How long has it been tax-exempt? Passed.

    Recognized by the IRS since July 2023.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated September 7, 2026.

  6. Is it in good standing with state regulators? Passed.

    Not on California's list of charities barred from soliciting. Other states are not yet checked.

    Source: May Not Operate or Solicit for Charitable Purposes list, California Attorney General, Registry of Charities and Fundraisers, file dated October 7, 2026.

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