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American Brain Foundation

EIN 41-1717098 · Minneapolis, MN

Public records show a registered, tax-exempt organization in good standing.

LegitimacyPassesRegistration and standingFinancial healthGood74 out of 100GovernanceStrong100 out of 100Impact evidenceDescribes programsHow well its results are evidenced

What it says it does

THE AMERICAN BRAIN FOUNDATION ACCELERATES BREAKTHROUGH RESEARCH ACROSS BRAIN DISEASES AND DISORDERS BY INVESTING IN INNOVATIVE SCIENCE, EARLY-CAREER INVESTIGATORS, AND CROSS-DISEASE DISCOVERIES THAT ADVANCE TREATMENTS, CURES, AND BRAIN HEALTH FOR ALL.

Income
$7.8 million
Spending
$11.0 million
Spent on programs
82%
Reserves
10.1 months of spending
Largest source of income
donations and private grants, 97%
Employees
15
Volunteers
48
Highest pay
$400,075, executive director

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Financial health

Good: 74 out of 100. Higher than 36% of charities in its peer group (medical research, $1m to $10m).

  • Reserves

    28 of 35

    Spendable reserves would cover 10.1 months of spending.

  • Debt

    16 of 20

    It owes 17% of what it owns.

  • Living within its means

    0 of 15

    Spending exceeded income by 41% of income.

  • Income trend

    15 of 15

    Income rose 26% on the year before.

  • Spending floor

    15 of 15

    82% of spending went to programs and raising each dollar of donations cost 17 cents.

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Governance

Strong: 100 out of 100. Higher than 64% of charities in its peer group (medical research, $1m to $10m).

  • Independent board

    25 of 25

    17 of 17 voting board members are independent.

  • Conflict of interest policy

    15 of 15

    Has a written conflict of interest policy.

  • Whistleblower policy

    8 of 8

    Has a written whistleblower policy.

  • Record keeping policy

    7 of 7

    Has a written policy on keeping and destroying records.

  • Board minutes

    5 of 5

    Keeps minutes of board meetings.

  • Board sees the tax return

    10 of 10

    Gave the board a copy of this return before filing it.

  • Pay set independently

    5 of 5

    Sets its chief executive's pay through independent review and comparison.

  • Independent check of accounts

    15 of 15

    Its accounts were audited by an independent accountant.

  • No reported misuse

    10 of 10

    Reports no diversion of assets, excess benefits or loans to insiders.

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Impact evidence

Describes programs. Its tax return describes what it does but we have found no measurable results in it.

Programs described in its return (2)
  1. $889,892 spent. THE FOUNDATION ADVANCED PUBLIC UNDERSTANDING OF BRAIN RESEARCH AND BRAIN HEALTH THROUGH EDUCATIONAL CONTENT, RESEARCH UPDATES, PATIENT AND CAREGIVER STORIES, PUBLIC EVENTS, AND DONOR ENGAGEMENT. THESE EFFORTS HELPED PEOPLE SEE THE CONNECTIONS AMONG BRAIN DISEASES, REDUCE STIGMA, AND UNDERSTAND THE URGENCY AND PROMISE OF RESEARCH. THROUGH ITS CURE ONE, CURE MANY APPROACH, THE FOUNDATION SHOWED HOW DISCOVERIES IN ONE BRAIN DISEASE CAN ACCELERATE PROGRESS ACROSS MANY, INSPIRING AWARENESS, ADVOCACY, AND PHILANTHROPIC SUPPORT.
  2. $8.1 million spent. IN 2025, THE FOUNDATION INVESTED IN RESEARCH ACROSS MULTIPLE BRAIN DISEASES THROUGH ITS NEXT GENERATION RESEARCH GRANTS AND CURE ONE, CURE MANY INITIATIVES. IT FUNDED EARLY-CAREER INVESTIGATORS AND INNOVATIVE PROJECTS IN ALS, ALD, ALZHEIMER'S AND AGE-RELATED COGNITIVE DECLINE, EPILEPSY, FRONTOTEMPORAL DEGENERATION, LEWY BODY DISEASES, MULTIPLE SCLEROSIS, NEUROMUSCULAR DISEASE, NEUROLOGICAL HEALTH DISPARITIES, PARKINSON'S DISEASE, PERIPHERAL NEUROPATHY, AND STROKE. THESE GRANTS HELP LAUNCH RESEARCH CAREERS; MORE THAN 95% OF NEARLY 330 FOUNDATION-FUNDED INVESTIGATORS HAVE SECURED FOLLOW-ON SUPPORT FROM NIH OR OTHER MAJOR FUNDERS. THE FOUNDATION ALSO ADVANCED TWO CROSS-DISEASE INITIATIVES TO TARGET SHARED MECHANISMS AND ACCELERATE DISCOVERIES FOR PATIENTS.

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Legitimacy checks

  1. Is it registered with the IRS? Passed.

    Listed in the IRS master file of tax-exempt organizations as a 501(c)(3) charitable organization.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  2. Has the IRS revoked its tax-exempt status? Passed.

    Not on the IRS automatic revocation list.

    Source: Automatic revocation of exemption list, Internal Revenue Service, file dated November 6, 2026.

  3. Are donations tax-deductible? Passed.

    On the IRS list of organizations eligible to receive tax-deductible contributions.

    Source: Publication 78 data: organizations eligible for tax-deductible contributions, Internal Revenue Service, file dated October 13, 2026.

  4. Is it keeping up with its IRS filings? Passed.

    Most recent return on file covers the year ending December 2025.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  5. How long has it been tax-exempt? Passed.

    Recognized by the IRS since May 1993.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  6. Is it in good standing with state regulators? Passed.

    Not on California's list of charities barred from soliciting. Other states are not yet checked.

    Source: May Not Operate or Solicit for Charitable Purposes list, California Attorney General, Registry of Charities and Fundraisers, file dated November 4, 2026.

  7. Could it be confused with another charity? Worth knowing.

    A much larger organization has a similar name: Americares Foundation Inc (Stamford, CT), EIN 06-1008595. If that is the one you meant, check the EIN before giving.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

Ratings and checks are our reading of public records, using the published method. They are not a statement about anyone's honesty. If you work for this organization, you can send corrections or results, confirm you want gifts through Veridonate, or ask to be removed from giving.