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Regenstrief Institute Inc

EIN 30-0007730 · Indianapolis, IN

Public records show a registered, tax-exempt organization in good standing.

LegitimacyPassesRegistration and standingFinancial healthGood82 out of 100GovernanceGood70 out of 100Impact evidenceDescribes programsHow well its results are evidenced

What it says it does

To improve health through research that enhances the quality and cost-effectiveness of health care, by functioning as a healthcare laboratory and community of scholars.

Income
$25.8 million
Spending
$27.4 million
Spent on programs
72%
Reserves
9.8 months of spending
Largest source of income
government grants, 52%
Employees
227
Volunteers
11
Highest pay
$1.3 million, board member

Source: Form 990 for the year ending June 30, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Financial health

Good: 82 out of 100. Higher than 77% of charities in its peer group (education, $10m to $100m).

  • Reserves

    28 of 35

    Spendable reserves would cover 9.8 months of spending.

  • Debt

    20 of 20

    It owes 8% of what it owns.

  • Living within its means

    4 of 15

    Spending exceeded income by 6% of income.

  • Income trend

    15 of 15

    Income rose 5% on the year before.

  • Spending floor

    15 of 15

    72% of spending went to programs and raising each dollar of donations cost 0 cents.

Source: Form 990 for the year ending June 30, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Governance

Good: 70 out of 100. Higher than 5% of charities in its peer group (education, $10m to $100m).

  • Independent board

    5 of 25

    3 of 11 voting board members are independent.

  • Conflict of interest policy

    15 of 15

    Has a written conflict of interest policy.

  • Whistleblower policy

    8 of 8

    Has a written whistleblower policy.

  • Record keeping policy

    7 of 7

    Has a written policy on keeping and destroying records.

  • Board minutes

    5 of 5

    Keeps minutes of board meetings.

  • Board sees the tax return

    0 of 10

    Did not give the board a copy of this return before filing it.

  • Pay set independently

    5 of 5

    Sets its chief executive's pay through independent review and comparison.

  • Independent check of accounts

    15 of 15

    Its accounts were audited by an independent accountant.

  • No reported misuse

    10 of 10

    Reports no diversion of assets, excess benefits or loans to insiders.

Source: Form 990 for the year ending June 30, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Impact evidence

Describes programs. Its tax return describes what it does but we have found no measurable results in it.

Programs described in its return (9)
  1. $7.1 million spent. Regenstrief Data Services - Supports innovative healthcare research by providing access to Regenstrief Institute data assets and informatics expertise. Regenstrief Data Services assists investigators across all stages of research, from study design and data analysis to algorithm validation and implementation. (Expenses $ 2,841,379 including grants of $ 0)(Revenue $ 1,702,922) The William M. Tierney Center for Health Services Research - Conducts multidisciplinary research in clinical and community settings to improve the delivery and outcomes of health care services through innovative use of health information and health information technology. (Expenses $ 2,231,675 including grants of $ 0)(Revenue $ 481,478) Center for Aging Research - Develop, test, and implement innovative strategies to improve the quality and efficiency of healthcare and self-care for medically and socially vulnerable older adults. Explore new models of care for late life depression, dementia, delirium and other common geriatric syndromes. Subject descriptive clinical and demographic data; ability to study clinical outcomes and guidance in regard to data security.
  2. $3.9 million spent. Center for Biomedical Informatics - Improving healthcare through informatics. Develop and apply health information technology solutions to generate knowledge about health, disease and treatment, help clinicians make optimal decisions, empower patients, and inform healthcare policy.
  3. $3.4 million spent. Health Data Standards (HDS) - Develops and maintains LOINC (Logical Observation Identifiers Names and Codes), a clinical terminology standard mandated for U.S. federal health programs and implemented internationally, and UCUM (Unified Code for Units of Measure) which supports consistent exchange of quantitative data in science, health care, and business. HDS also convenes global stakeholders to advance interoperable health data standards that enable effective data exchange, promote their adoption, and help shape the scientific and policy landscape related to research, public health, and patient care. (Expenses $ 2,841,379 including grants of $ 0)(Revenue $ 1,702,922) The William M. Tierney Center for Health Services Research - Conducts multidisciplinary research in clinical and community settings to improve the delivery and outcomes of health care services through innovative use of health information and health information technology. (Expenses $ 2,231,675 including grants of $ 0)(Revenue $ 481,478) Center for Aging Research - Develop, test, and implement innovative strategies to improve the quality and efficiency of healthcare and self-care for medically and socially vulnerable older adults. Explore new models of care for late life depression, dementia, delirium and other common geriatric syndromes. Subject descriptive clinical and demographic data; ability to study clinical outcomes and guidance in regard to data security.
  4. $2.8 million spent. The William M. Tierney Center for Health Services Research - Conducts multidisciplinary research in clinical and community settings to improve the delivery and outcomes of health care services through innovative use of health information and health information technology.
  5. $2.2 million spent. Center for Aging Research - Develop, test, and implement innovative strategies to improve the quality and efficiency of healthcare and self-care for medically and socially vulnerable older adults. Explore new models of care for late life depression, dementia, delirium and other common geriatric syndromes. Subject descriptive clinical and demographic data; ability to study clinical outcomes and guidance in regard to data security.
  6. IU Institute Support & IU Share Support
  7. Miscellaneous Revenue
  8. (Expenses $ 0 including grants of $ 0)(Revenue $ 800,000) IU Institute Support & IU Share Support
  9. (Expenses $ 0 including grants of $ 0)(Revenue $ 208,812) Miscellaneous Revenue

Source: Form 990 for the year ending June 30, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Legitimacy checks

  1. Is it registered with the IRS? Passed.

    Listed in the IRS master file of tax-exempt organizations as a 501(c)(3) charitable organization.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  2. Has the IRS revoked its tax-exempt status? Passed.

    Not on the IRS automatic revocation list.

    Source: Automatic revocation of exemption list, Internal Revenue Service, file dated October 13, 2026.

  3. Are donations tax-deductible? Passed.

    On the IRS list of organizations eligible to receive tax-deductible contributions.

    Source: Publication 78 data: organizations eligible for tax-deductible contributions, Internal Revenue Service, file dated October 13, 2026.

  4. Is it keeping up with its IRS filings? Passed.

    Most recent return on file covers the year ending June 2025.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  5. How long has it been tax-exempt? Passed.

    Recognized by the IRS since June 2002.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  6. Is it in good standing with state regulators? Passed.

    Not on California's list of charities barred from soliciting. Other states are not yet checked.

    Source: May Not Operate or Solicit for Charitable Purposes list, California Attorney General, Registry of Charities and Fundraisers, file dated October 21, 2026.

Ratings and checks are our reading of public records, using the published method. They are not a statement about anyone's honesty. If you work for this organization, you can send corrections or results, confirm you want gifts through Veridonate, or ask to be removed from giving.