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J David Gladstone Institutes

EIN 23-7203666 · San Francisco, CA

Public records show a registered, tax-exempt organization in good standing.

LegitimacyPassesRegistration and standingFinancial healthWeak40 out of 100GovernanceGood70 out of 100Impact evidenceDescribes programsHow well its results are evidenced

Points to look into

  • It reported loans to or from officers, directors or other insiders.

These come from the organization's own tax return. There may be a good explanation; ask the charity.

What it says it does

TO DRIVE A NEW ERA OF DISCOVERY IN DISEASE ORIENTED SCIENCE AND TO MENTOR TOMORROW'S LEADERS IN AN INSPIRING AND DIVERSE ENVIRONMENT.

Income
$119.2 million
Spending
$144.8 million
Spent on programs
85%
Reserves
2.1 months of spending
Largest source of income
fees for its services, 79%
Employees
593
Volunteers
90
Highest pay
$1.2 million, president

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Financial health

Weak: 40 out of 100. Higher than 11% of charities in its peer group (medical research, over $100m).

  • Reserves

    10 of 35

    Spendable reserves would cover 2.1 months of spending.

  • Debt

    5 of 20

    It owes 55% of what it owns.

  • Living within its means

    0 of 15

    Spending exceeded income by 22% of income.

  • Income trend

    10 of 15

    Income fell 0% on the year before.

  • Spending floor

    15 of 15

    85% of spending went to programs and raising each dollar of donations cost 15 cents.

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Governance

Good: 70 out of 100. Higher than 0% of charities in its peer group (medical research, over $100m).

  • Independent board

    5 of 25

    0 of 3 voting board members are independent.

  • Conflict of interest policy

    15 of 15

    Has a written conflict of interest policy.

  • Whistleblower policy

    8 of 8

    Has a written whistleblower policy.

  • Record keeping policy

    7 of 7

    Has a written policy on keeping and destroying records.

  • Board minutes

    5 of 5

    Keeps minutes of board meetings.

  • Board sees the tax return

    10 of 10

    Gave the board a copy of this return before filing it.

  • Pay set independently

    5 of 5

    Sets its chief executive's pay through independent review and comparison.

  • Independent check of accounts

    15 of 15

    Its accounts were audited by an independent accountant.

  • No reported misuse

    0 of 10

    Reports at least one of: diversion of assets, excess benefits, loans to insiders.

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Impact evidence

Describes programs. Its tax return describes what it does but we have found no measurable results in it.

Programs described in its return (4)
  1. $44.0 million spent. THE INSTITUTE OF NEUROLOGICAL DISEASE MAINTAINS A STRONG FOCUS ON NEURODEGENERATIVE AND NEUROINFLAMMATORY DISEASES, INCLUDING ALZHEIMER'S DISEASE AND OTHER DEMENTIAS, PARKINSON'S DISEASE, AMYOTROPHIC LATERAL SCLEROSIS (ALS), AND MULTIPLE SCLEROSIS. THE INVESTIGATORS ARE SEARCHING FOR COMMON THREADS THAT WILL ALLOW THEM TO IDENTIFY THERAPEUTIC INTERVENTIONS THAT MIGHT BENEFIT MULTIPLE CONDITIONS. THEY ARE USING UNCONVENTIONAL APPROACHES TO IDENTIFY SUCH MULTI-FACETED SOLUTIONS, WHILE ALSO LEVERAGING CAPABILITIES IN REGENERATIVE AND PERSONALIZED MEDICINE.
  2. $26.7 million spent. THE INSTITUTE OF VIROLOGY HAS MADE SIGNIFICANT CONTRIBUTIONS TO FIGHT HIV/AIDS, SARS-COV-2, HEPATITIS C, ZIKA, AND CYTOMEGALOVIRUS INFECTIONS LEADING TO GLOBAL AND GROUNDBREAKING EFFORTS IN HIV PREVENTION AND CURE. ITS STATE OF THE ART BSL3 LABORATORIES HAVE ALLOWED GLADSTONE TO DO GROUNDBREAKING WORK IN UNDERSTANDING THE COVID-19 VIRUS AND OTHER VIRUS DRIVEN DISEASES. BY FOCUSING ON PREVENTION, DIAGNOSIS, AND THERAPEUTICS, THE INSTITUTE AIMS TO DEVELOP PROACTIVE STRATEGIES TO TACKLE CURRENT AND FUTURE PANDEMICS.
  3. $23.6 million spent. THE INSTITUTE OF CARDIOVASCULAR DISEASE LEVERAGES IMPORTANT GENETIC, DEVELOPMENTAL, CHEMICAL, BIOLOGICAL SYSTEMS, COMPUTATIONAL, AND ENGINEERING APPROACHES TO STUDY HEART DISEASE AND STEM CELL BIOLOGY.
  4. $29.3 million spent. THE GLADSTONE INSTITUTE OF DATA SCIENCE AND BIOTECHNOLOGY INVESTS IN TALENT TO CREATE NEW WAYS TO ANALYZE AND INTEGRATE DATASETS, INCLUDING MACHINE LEARNING APPROACHES THAT LEVERAGE THE RAPID ADVANCES IN ARTIFICIAL INTELLIGENCE. IT WILL BE THE HOME FOR DEVELOPMENT OF NEW TECHNOLOGIES THAT CAN ACCELERATE DISCOVERY IN ALL AREAS OF INVESTIGATION AT GLADSTONE. GLADSTONE - UCSF INSTITUTE OF GENOMIC IMMUNOLOGY BLENDS THE LATEST GENOMICS AND GENOME ENGINEERING TECHNOLOGIES WITH IMMUNOLOGY RESEARCH TO ENGINEER THE HUMAN IMMUNE SYSTEM FOR THERAPEUTIC BENEFIT.

Source: Form 990 for the year ending December 31, 2024, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Legitimacy checks

  1. Is it registered with the IRS? Passed.

    Listed in the IRS master file of tax-exempt organizations as a 501(c)(3) charitable organization.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated September 7, 2026.

  2. Has the IRS revoked its tax-exempt status? Passed.

    Not on the IRS automatic revocation list.

    Source: Automatic revocation of exemption list, Internal Revenue Service, file dated September 30, 2026.

  3. Are donations tax-deductible? Passed.

    On the IRS list of organizations eligible to receive tax-deductible contributions.

    Source: Publication 78 data: organizations eligible for tax-deductible contributions, Internal Revenue Service, file dated September 10, 2026.

  4. Is it keeping up with its IRS filings? Passed.

    Most recent return on file covers the year ending December 2024.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated September 7, 2026.

  5. How long has it been tax-exempt? Passed.

    Recognized by the IRS since June 1973.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated September 7, 2026.

  6. Is it in good standing with state regulators? Passed.

    Not on California's list of charities barred from soliciting. Other states are not yet checked.

    Source: May Not Operate or Solicit for Charitable Purposes list, California Attorney General, Registry of Charities and Fundraisers, file dated October 7, 2026.

Ratings and checks are our reading of public records, using the published method. They are not a statement about anyone's honesty. If you work for this organization, you can send corrections or results, confirm you want gifts through Veridonate, or ask to be removed from giving.