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National Disease Research Interchange

EIN 23-2213205 · Philadelphia, PA

Public records show a registered, tax-exempt organization in good standing.

LegitimacyPassesRegistration and standingFinancial healthFair53 out of 100GovernanceStrong100 out of 100Impact evidenceDescribes programsHow well its results are evidenced

What it says it does

THE MISSION OF NDRI IS TO PROVIDE HUMAN BIOSPECIMENS WORLDWIDE TO ADVANCE BIOMEDICAL/BIOSCIENCE RESEARCH AND DEVELOPMENT AND EDUCATION IN THE LIFE SCIENCES.

Income
$12.8 million
Spending
$13.0 million
Spent on programs
75%
Reserves
1 months of spending
Largest source of income
government grants, 65%
Employees
51
Volunteers
16
Highest pay
$531,022, president & ceo

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Financial health

Fair: 53 out of 100. Higher than 25% of charities in its peer group (medical research, $10m to $100m).

  • Reserves

    10 of 35

    Spendable reserves would cover 1.0 months of spending.

  • Debt

    5 of 20

    It owes 67% of what it owns.

  • Living within its means

    8 of 15

    Spending exceeded income by 1% of income.

  • Income trend

    15 of 15

    Income rose 14% on the year before.

  • Spending floor

    15 of 15

    75% of spending went to programs and raising each dollar of donations cost 0 cents.

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Governance

Strong: 100 out of 100. Higher than 45% of charities in its peer group (medical research, $10m to $100m).

  • Independent board

    25 of 25

    16 of 17 voting board members are independent.

  • Conflict of interest policy

    15 of 15

    Has a written conflict of interest policy.

  • Whistleblower policy

    8 of 8

    Has a written whistleblower policy.

  • Record keeping policy

    7 of 7

    Has a written policy on keeping and destroying records.

  • Board minutes

    5 of 5

    Keeps minutes of board meetings.

  • Board sees the tax return

    10 of 10

    Gave the board a copy of this return before filing it.

  • Pay set independently

    5 of 5

    Sets its chief executive's pay through independent review and comparison.

  • Independent check of accounts

    15 of 15

    Its accounts were audited by an independent accountant.

  • No reported misuse

    10 of 10

    Reports no diversion of assets, excess benefits or loans to insiders.

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Impact evidence

Describes programs. Its tax return describes what it does but we have found no measurable results in it.

Programs described in its return (3)
  1. $6.9 million spent. HUMAN TISSUE AND RESOURCE FOR RESEARCH: NDRI RECEIVED A FEDERAL AWARD FOR THE HUMAN TISSUE AND ORGAN RESOURCE FOR THE PROCUREMENT AND DISTRIBUTION OF NORMAL AND DISEASED HUMAN ORGANS AND TISSUES TO ADVANCE BIOMEDICAL SCIENCE.
  2. $901,436 spent. PARTNER PROGRAM: COORDINATES VARIOUS HUMAN ORGAN AND TISSUE PROCUREMENT PROGRAMS WITH THE PHARMACEUTICAL AND BIOTECHNOLOGY INDUSTRIES TO ACCELERATE RESEARCH AND DEVELOPMENT. SEVERAL OF THESE PROGRAMS HAVE LED TO THE DEVELOPMENT OF TREATMENTS FOR MEDICAL CONDITIONS SUCH AS LUNG DISEASE, DIABETES, AND CANCER, TO NAME ONLY A FEW. OTHER PARTNER PROGRAMS HAVE LED TO THE CREATION OF RESEARCH TOOLS FOR USE IN NUMEROUS TOXICOLOGY AND DRUG DISCOVERY PLATFORMS.
  3. $1.9 million spent. RESEARCH COLLABORATIONS WITH FOUNDATION AND PATIENT ADVOCACY GROUPS (PAG): NDRI MAINTAINS COLLABORATIONS WITH A VARIETY OF DIFFERENT FOUNDATION AND PATIENT ADVOCACY GROUPS FOCUSED ON THE ADVANCEMENT OF RESEARCH IN EACH OF THEIR RESPECTIVE AREAS OF INTEREST. THESE COLLABORATIONS BRING TOGETHER PATIENTS, PAGS, FOUNDATIONS, NDRI AND THE PHARMACEUTICAL INDUSTRY TO HELP ADVANCE R&D UTILIZING CRITICAL HUMAN BIOSPECIMENS GIFTED BY PATIENTS/DONORS.

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Legitimacy checks

  1. Is it registered with the IRS? Passed.

    Listed in the IRS master file of tax-exempt organizations as a 501(c)(3) charitable organization.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  2. Has the IRS revoked its tax-exempt status? Passed.

    Not on the IRS automatic revocation list.

    Source: Automatic revocation of exemption list, Internal Revenue Service, file dated October 13, 2026.

  3. Are donations tax-deductible? Passed.

    On the IRS list of organizations eligible to receive tax-deductible contributions.

    Source: Publication 78 data: organizations eligible for tax-deductible contributions, Internal Revenue Service, file dated October 13, 2026.

  4. Is it keeping up with its IRS filings? Passed.

    Most recent return on file covers the year ending December 2025.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  5. How long has it been tax-exempt? Passed.

    Recognized by the IRS since August 1982.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  6. Is it in good standing with state regulators? Passed.

    Not on California's list of charities barred from soliciting. Other states are not yet checked.

    Source: May Not Operate or Solicit for Charitable Purposes list, California Attorney General, Registry of Charities and Fundraisers, file dated October 21, 2026.

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