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Regenerative Research Foundation

EIN 20-3654626 · Albany, NY

Public records show a registered, tax-exempt organization in good standing.

LegitimacyPassesRegistration and standingFinancial healthGood83 out of 100GovernanceStrong100 out of 100Impact evidenceDescribes programsHow well its results are evidenced

What it says it does

THE PRINCIPAL MISSION OF THE REGENERATIVE RESEARCH FOUNDATION IS TO DEVELOP REGENERATIVE STEM CELL THERAPIES FOR DISEASES OF THE CENTRAL NERVOUS SYSTEM (CNS): THE BRAIN, SPINAL CORD, AND RETINA.

Income
$8.0 million
Spending
$7.1 million
Spent on programs
87%
Reserves
8.6 months of spending
Largest source of income
government grants, 83%
Employees
43
Volunteers
16
Highest pay
$194,980, executive & scientific director

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Financial health

Good: 83 out of 100. Higher than 49% of charities in its peer group (medical research, $1m to $10m).

  • Reserves

    28 of 35

    Spendable reserves would cover 8.6 months of spending.

  • Debt

    10 of 20

    It owes 32% of what it owns.

  • Living within its means

    15 of 15

    Income exceeded spending by 11% of income.

  • Income trend

    15 of 15

    Income rose 14% on the year before.

  • Spending floor

    15 of 15

    87% of spending went to programs and raising each dollar of donations cost 0 cents.

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Governance

Strong: 100 out of 100. Higher than 64% of charities in its peer group (medical research, $1m to $10m).

  • Independent board

    25 of 25

    6 of 7 voting board members are independent.

  • Conflict of interest policy

    15 of 15

    Has a written conflict of interest policy.

  • Whistleblower policy

    8 of 8

    Has a written whistleblower policy.

  • Record keeping policy

    7 of 7

    Has a written policy on keeping and destroying records.

  • Board minutes

    5 of 5

    Keeps minutes of board meetings.

  • Board sees the tax return

    10 of 10

    Gave the board a copy of this return before filing it.

  • Pay set independently

    5 of 5

    Sets its chief executive's pay through independent review and comparison.

  • Independent check of accounts

    15 of 15

    Its accounts were audited by an independent accountant.

  • No reported misuse

    10 of 10

    Reports no diversion of assets, excess benefits or loans to insiders.

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Impact evidence

Describes programs. Its tax return describes what it does but we have found no measurable results in it.

Programs described in its return (3)
  1. $1.0 million spent. DESPITE MANY CHALLENGES IN FISCAL YEAR 2025 THE REGENERATIVE RESEARCH FOUNDATION CONTINUED TO PURSUE ITS RESEARCH MISSION. DURING THE YEAR FOUNDATION RESEARCHERS PUBLISHED THIRTEEN ARTICLES IN PROMINENT SCIENTIFIC JOURNALS REPORTING THE RESULTS OF THEIR INVESTIGATIONS INTO NEURODEGENERATIVE DISEASES SUCH AS DEMENTIA, MACULAR DEGENERATION AND POTENTIAL TREATMENTS FOR NEURODEGENERATIVE DISEASES. THESE PUBLICATIONS ARE AVAILABLE TO THE RESEARCH COMMUNITY AND GENERAL PUBLIC FREE OF CHARGE THROUGH THE NATIONAL LIBRARY OF MEDICINE OPEN ACCESS REPOSITORY. THE FOUNDATION RESEARCHERS CONTINUE TO PREPARE FUNDING APPLICATIONS WHICH WILL SUPPORT THEIR RESEARCH ACTIVITIES. THE FOUNDATION CONTINUED TO DEVELOP AND IMPROVE ITS PRODUCTION OF HUMAN STEM CELL ORGANOID MODELS AS AN ALTERNATIVE TO THE USE OF ANIMAL MODELS. THESE EFFORTS ARE ENDORSED BY THE NIH AND FDA COMPLEMENT-ARIE INITIATIVES THAT PROMOTE NEW APPROACH METHODOLOGY (NAM) TO REDUCE ANIMAL USE IN DRUG DEVELOPMENT. THE FOUNDATION'S CORE FACILITY, NEURACELL, CONTINUES TO PROVIDE BRAIN REGION-SPECIFIC ORGANOIDS TO RESEARCHERS AROUND THE COUNTRY.
  2. $1.0 million spent. THE CONTINUING PHASE 1/2A CLINICAL TRIAL TREATED ITS 12TH SUBJECT COMPLETING THE SECOND COHORT OF AN 18-SUBJECT TRIAL. THE FOUNDATION'S SCIENTIFIC DIRECTOR, DR. SALLY TEMPLE-STERN, DELIVERED THE CLOSING KEYNOTE ADDRESS AT THE 2026 ASSOCIATION FOR RESEARCH IN VISION AND OPHTHALMOLOGY MEETING (THE MAJOR MEETING FOR OPHTHALMIC RESEARCH). THE SAFETY AND EFFICACY RESULTS OF THE LOW DOSE PHASE OF THE TRIAL WERE PUBLISHED DURING THE YEAR 2025.
  3. $4.1 million spent. THE ALZHEIMER'S DISEASE AND RELATED DEMENTIAS RESEARCH PROGRAM CONTINUES ITS MISSION TO EXPAND THE UNDERSTANDING AND DEVELOPMENT OF A POTENTIAL TREATMENT FOR THESE NEURODEGENERATIVE DISEASES. THE INSTITUTE CONTINUES TO SERVE AS THE LEAD ORGANIZATION FOR A CONSORTIUM OF INSTITUTIONS AND INVESTIGATORS FUNDED BY THE NATIONAL INSTITUTES OF HEALTH AND OTHER PRIVATE FOUNDATIONS WHICH IS FOCUSED ON IDENTIFYING GENES ASSOCIATED WITH THE DEVELOPMENT OF DEMENTIA. THE FOUNDATION CONTINUES ITS SEARCH FOR A BIOTECH PARTNER TO SUPPORT RESEARCH AND DEVELOPMENT OF A PROMISING NEURODEGENERATIVE DISEASE TREATMENT UNDER DEVELOPMENT BY THE FOUNDATION.

Source: Form 990 for the year ending December 31, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Legitimacy checks

  1. Is it registered with the IRS? Passed.

    Listed in the IRS master file of tax-exempt organizations as a 501(c)(3) charitable organization.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  2. Has the IRS revoked its tax-exempt status? Passed.

    Not on the IRS automatic revocation list.

    Source: Automatic revocation of exemption list, Internal Revenue Service, file dated November 6, 2026.

  3. Are donations tax-deductible? Passed.

    On the IRS list of organizations eligible to receive tax-deductible contributions.

    Source: Publication 78 data: organizations eligible for tax-deductible contributions, Internal Revenue Service, file dated October 13, 2026.

  4. Is it keeping up with its IRS filings? Passed.

    Most recent return on file covers the year ending December 2025.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  5. How long has it been tax-exempt? Passed.

    Recognized by the IRS since November 2007.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated October 13, 2026.

  6. Is it in good standing with state regulators? Passed.

    Not on California's list of charities barred from soliciting. Other states are not yet checked.

    Source: May Not Operate or Solicit for Charitable Purposes list, California Attorney General, Registry of Charities and Fundraisers, file dated November 4, 2026.

Ratings and checks are our reading of public records, using the published method. They are not a statement about anyone's honesty. If you work for this organization, you can send corrections or results, confirm you want gifts through Veridonate, or ask to be removed from giving.