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Passes our checks

Xenobe Research Institute

EIN 20-1624945 · San Diego, CA

Public records show a registered, tax-exempt organization in good standing.

LegitimacyPassesRegistration and standingFinancial healthStrong100 out of 100GovernanceFair56 out of 100Impact evidenceDescribes programsHow well its results are evidenced

What it says it does

The Xenobe Research Institute conducts research on natural and synthetic small molecule therapeutics with the ultimate goal of discovering and ultimately translating new materials for clinical trials. Funds were obtained from two projects one supported by the NIH and the other by Terra Bioworks

Income
$174,939
Spending
$131,801
Spent on programs
100%
Reserves
24.7 months of spending
Largest source of income
government grants, 85%
Employees
1
Volunteers
0
Highest pay
$44,352, president

Source: Form 990 for the year ending June 30, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Financial health

Strong: 100 out of 100.

  • Reserves

    35 of 35

    Spendable reserves would cover 24.7 months of spending.

  • Debt

    20 of 20

    It owes 0% of what it owns.

  • Living within its means

    15 of 15

    Income exceeded spending by 25% of income.

  • Income trend

    15 of 15

    Income rose 185% on the year before.

  • Spending floor

    15 of 15

    100% of spending went to programs and raising each dollar of donations cost 0 cents.

Source: Form 990 for the year ending June 30, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Governance

Fair: 56 out of 100.

  • Independent board

    0 of 25

    0 of 2 voting board members are independent.

  • Conflict of interest policy

    15 of 15

    Has a written conflict of interest policy.

  • Whistleblower policy

    8 of 8

    Has a written whistleblower policy.

  • Record keeping policy

    0 of 7

    Reports no written policy on keeping and destroying records.

  • Board minutes

    5 of 5

    Keeps minutes of board meetings.

  • Board sees the tax return

    10 of 10

    Gave the board a copy of this return before filing it.

  • Pay set independently

    0 of 5

    Reports no independent review process for its chief executive's pay.

  • No reported misuse

    10 of 10

    Reports no diversion of assets, excess benefits or loans to insiders.

Source: Form 990 for the year ending June 30, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Impact evidence

Describes programs. Its tax return describes what it does but we have found no measurable results in it.

Programs described in its return (3)
  1. $104,912 spent. National Institutes of Health Grant R21NS128597. While well established as clinical targets, the lack of molecular probes to the large immunophilins continues to inhibit our ability to evaluate and drug them clinically. This program explores the development of a general platform to discover probes that target specific domains within a neurological protein. Using cyclophilin 40 (Cyp40), FK506-binding proteins FKBP51 and FKBP52, our team seeks to define critically needed reagents to understand the role of the `large immunophilin' family in neurological disease. We began studies on our recently funded R21 program and have reported signficance success within our initial year of funding.The revenue generated will be used for the latter half of the program. A two year award was provided within this funding period. These funds to cover salaries, research supplies, instrument time, and equipment access to complete these studies.
  2. $26,889 spent. Terra Bioworks. Granted funding was provided to support small molecule isolation and structure elucidation efforts. These funds were used to cover research supplies, instrument time, and equipment access to complete these studies.
  3. None

Source: Form 990 for the year ending June 30, 2025, filed with the Internal Revenue Service. Rating method 2026.2. How we rate

Legitimacy checks

  1. Is it registered with the IRS? Passed.

    Listed in the IRS master file of tax-exempt organizations as a 501(c)(3) charitable organization.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated September 7, 2026.

  2. Has the IRS revoked its tax-exempt status? Passed.

    Not on the IRS automatic revocation list.

    Source: Automatic revocation of exemption list, Internal Revenue Service, file dated September 30, 2026.

  3. Are donations tax-deductible? Passed.

    On the IRS list of organizations eligible to receive tax-deductible contributions.

    Source: Publication 78 data: organizations eligible for tax-deductible contributions, Internal Revenue Service, file dated September 10, 2026.

  4. Is it keeping up with its IRS filings? Passed.

    Most recent return on file covers the year ending June 2025.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated September 7, 2026.

  5. How long has it been tax-exempt? Passed.

    Recognized by the IRS since October 2005.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated September 7, 2026.

  6. Is it in good standing with state regulators? Passed.

    Not on California's list of charities barred from soliciting. Other states are not yet checked.

    Source: May Not Operate or Solicit for Charitable Purposes list, California Attorney General, Registry of Charities and Fundraisers, file dated October 7, 2026.

  7. Could it be confused with another charity? Worth knowing.

    A much larger organization has a similar name: Arc Research Institute (Palo Alto, CA), EIN 87-1920284. If that is the one you meant, check the EIN before giving.

    Source: Exempt Organizations Business Master File, Internal Revenue Service, file dated September 7, 2026.

Ratings and checks are our reading of public records, using the published method. They are not a statement about anyone's honesty. If you work for this organization, you can send corrections or results, confirm you want gifts through Veridonate, or ask to be removed from giving.